Configuring Windows Vista to use local DNS server

In the Windows Control Panel, under "Network and Internet", select "View network status and tasks":

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Click the "Manage network connections" task:

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Right-click your Internet connection's icon and select "Properties":

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Select the "Internet Protocol Version 4 (TCP/IPv4)" item, and click the "Properties" button:

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Select "Use the following DNS server addresses", and enter the IP address of the local DNS server (*) as the Preferred DNS server:

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Finally click the "OK" in this and the previous dialogs to save your changes.

(*) The DNS server IP address must match an IP address that Simple DNS Plus is configured to listen on in the Options dialog / DNS / Inbound Requests section.
If you are configuring the computer which Simple DNS Plus is running on, you can use 127.0.0.1 (the "localhost" address) - otherwise you must use an IP address which is accessible over the local area network.

NOTE: We also recommend disabling the "DNS Client" service

REFERENCES:
For more information, please see the following knowledge base articles:

KB Article Disabling the Windows "DNS Client" service
KB Article Configuring Windows to use local DNS server

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